Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridazine SCHEMBL10840851 | 0.90 | CES2 (0.32) | NAPRTLMNAP4HTML3MBTL1HCAR2 | |
| Pyridazine SCHEMBL7889331 | 0.86 | CA1 (0.39) | NAPRTLMNAP4HTML3MBTL1HCAR2 | |
| Oxalic Acid SCHEMBL27823009 | 0.83 | NAPRT (0.36) | NAPRTLMNAP4HTML3MBTL1HCAR2 | |
| Pyridazine SCHEMBL30071072 | 0.80 | FFAR3 (0.47) | NAPRTLMNAP4HTML3MBTL1HCAR2 | |
| Pyridazine SCHEMBL20893379 | 0.80 | ACHE (0.47) | NAPRTLMNAP4HTML3MBTL1HCAR2 | |
| Pyridazine SCHEMBL28630845 | 0.80 | FFAR3 (0.47) | NAPRTLMNAP4HTML3MBTL1HCAR2 | |
| Pyridazine SCHEMBL9257443 | 0.80 | NAPRT (0.35) | NAPRTLMNAP4HTML3MBTL1HCAR2 | |
| Pyridine SCHEMBL936385 | 0.80 | NAPRT (0.60) | NAPRTLMNAP4HTML3MBTL1HCAR2 | |
| Pyridine SCHEMBL9851406 | 0.80 | NAPRT (0.60) | NAPRTLMNAP4HTML3MBTL1HCAR2 | |
| Pyridazine SCHEMBL2162869 | 0.80 | FFAR3 (0.47) | NAPRTLMNAP4HTML3MBTL1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763303-A1 | SUBSTITUTED PYRIDAZINE CARBOXAMIDES AND DERIVATIVES THEREOF | Bayer CropScience Aktiengesellschaft (DE) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006000333-A1 | SUBSTITUTED PYRIDAZINE CARBOXAMIDES AND DERIVATIVES THEREOF | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | WO | disclosed |