⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471718 | 0.81 | LMNA (0.32) | — | |
| SCHEMBL6083736 | 0.72 | CYP11B2 (0.34) | — | |
| SCHEMBL10411212 | 0.70 | — | — | |
| SCHEMBL558602 | 0.68 | DRD2 (0.44) | — | |
| SCHEMBL6031056 | 0.68 | LMNA (0.38) | — | |
| SCHEMBL558130 | 0.68 | PSMB8 (0.35) | — | |
| SCHEMBL4574526 | 0.68 | MAPT (0.36) | — | |
| SCHEMBL558555 | 0.67 | PSMB8 (0.44) | — | |
| SCHEMBL558291 | 0.67 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL6098342 | 0.67 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631286-A4 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2007-08-29 | — | — | EP | claimed |
| EP-1631286-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2006-03-08 | — | — | EP | claimed |
| WO-2004110993-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-23 | — | — | WO | claimed |
| EP-1631286-A4 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2007-08-29 | — | — | EP | disclosed |
| EP-1631286-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004110993-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-23 | — | — | WO | disclosed |