Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6083736 | 0.70 | CYP11B2 (0.34) | — | |
| SCHEMBL558602 | 0.69 | DRD2 (0.44) | — | |
| SCHEMBL5217048 | 0.68 | — | — | |
| SCHEMBL8518157 | 0.68 | NUDT1 (0.40) | MAPTTDP1SMN1; SMN2ALDH1A1ERN1 | |
| SCHEMBL4655299 | 0.67 | MAPT (0.66) | MAPTTDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30683723 | 0.66 | ERN1 (0.48) | MAPTTDP1SMN1; SMN2ALDH1A1ERN1 | |
| SCHEMBL4471718 | 0.66 | LMNA (0.32) | MAPTSMN1; SMN2 | |
| SCHEMBL8951248 | 0.65 | MAPT (0.44) | MAPTTDP1SMN1; SMN2ALDH1A1ERN1 | |
| SCHEMBL27288856 | 0.65 | SMN1; SMN2 (0.51) | MAPTTDP1SMN1; SMN2ALDH1A1ERN1 | |
| SCHEMBL7744554 | 0.65 | MAPT (0.53) | MAPTTDP1SMN1; SMN2ALDH1A1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047883-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-04-24 | — | — | WO | disclosed |