Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471718 | 0.77 | LMNA (0.32) | LMNAMAPT | |
| SCHEMBL541947 | 0.69 | MEN1 (0.49) | LMNAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL30209785 | 0.69 | MEN1 (0.49) | LMNAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL5217048 | 0.68 | — | — | |
| SCHEMBL18753187 | 0.67 | RAB9A (0.44) | LMNAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL31149 | 0.64 | KMT2A (0.49) | LMNAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL6083736 | 0.64 | CYP11B2 (0.34) | — | |
| SCHEMBL23770851 | 0.64 | MTNR1B (0.41) | LMNAMEN1MAPTKMT2A | |
| SCHEMBL558602 | 0.63 | DRD2 (0.44) | — | |
| SCHEMBL4574526 | 0.63 | MAPT (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148869-A1 | Halogenated biaryl heterocyclic compounds and methods of making and using the same | CHEN SHILI | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148869-A1 | Halogenated biaryl heterocyclic compounds and methods of making and using the same | PCNA, PROKR1, BCOR | LMNA 2009/4885MEN1 1715/4885MAPT 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.