Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.58 |
| ▸ | COPS5 | Q92905 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034370 | 0.88 | COPS5 (0.54) | FBP1COPS5ALDH1A1CYP1A2HRH2 | |
| SCHEMBL1002345 | 0.85 | COPS5 (0.54) | FBP1COPS5ALDH1A1SMN1; SMN2CYP1A2 | |
| Bromide SCHEMBL7136559 | 0.84 | COPS5 (0.52) | FBP1COPS5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL27765071 | 0.81 | COPS5 (0.55) | FBP1COPS5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL3095838 | 0.81 | FBP1 (0.66) | FBP1COPS5ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL31661345 | 0.80 | FBP1 (0.72) | FBP1COPS5ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL30567598 | 0.77 | COPS5 (0.57) | FBP1COPS5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL4130111 | 0.75 | FBP1 (1.00) | FBP1COPS5ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5221270 | 0.73 | ALDH1A1 (0.44) | FBP1COPS5ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18337696 | 0.71 | ALDH1A1 (0.50) | FBP1COPS5ALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525193-B1 | ACYLAMINOTHIAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2007-12-26 | — | — | EP | disclosed |
| EP-1525193-A2 | ACYLAMINOTHIAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004009565-A2 | ACYLAMINOTHIAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2004-01-29 | — | — | WO | disclosed |