Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821918 | 0.89 | GABRP (0.50) | ALDH1A1CYP1A2HPGDHSD17B10MAPT | |
| SCHEMBL11338473 | 0.88 | GABRP (0.45) | ALDH1A1CYP1A2HPGDHSD17B10MAPT | |
| SCHEMBL1539908 | 0.87 | ALDH1A1 (0.45) | ALDH1A1CYP1A2HPGDHSD17B10MAPT | |
| SCHEMBL9369067 | 0.81 | L3MBTL1 (0.40) | ALDH1A1HPGDHSD17B10MAPTADORA2A | |
| SCHEMBL9644279 | 0.81 | GPR35 (0.38) | ALDH1A1HPGDGABRPGABRDGABRA1 | |
| SCHEMBL9643784 | 0.81 | ALDH1A1 (0.36) | ALDH1A1HPGDHSP90AA1TSHRAGTR1 | |
| SCHEMBL3618179 | 0.81 | ALDH1A1 (0.42) | ALDH1A1CYP1A2HPGDHSD17B10MAPT | |
| SCHEMBL31661300 | 0.81 | ALDH1A1 (0.41) | ALDH1A1CYP1A2HPGDHSD17B10FBP1 | |
| SCHEMBL3100377 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP1A2HPGDHSD17B10FBP1 | |
| SCHEMBL9644174 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525193-B1 | ACYLAMINOTHIAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2007-12-26 | — | — | EP | disclosed |
| EP-1525193-A2 | ACYLAMINOTHIAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004009565-A2 | ACYLAMINOTHIAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2004-01-29 | — | — | WO | disclosed |