SCHEMBL5219307

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5213833	0.83	KDM4E (0.43)	CDK5CDK5R1KMT2AMEN1CCNA2
	SCHEMBL11910637	0.79	DAGLA (0.55)	SLC6A2SLC6A4SLC6A3DAGLAALDH1A1
	SCHEMBL14422264	0.77	SMN1; SMN2 (0.47)	ALDH1A1NPC1RAB9APOLBMAPT
	SCHEMBL393999	0.76	DAGLA (0.42)	SLC6A2SLC6A4SLC6A3DAGLACACNA1G
	SCHEMBL14422265	0.76	HDAC1 (0.43)	ALDH1A1NPC1RAB9AKMT2AMEN1
	SCHEMBL15001329	0.75	SLC6A2 (0.45)	SLC6A2SLC6A4SLC6A3DAGLACACNA1G
	SCHEMBL16130104	0.75	DAGLA (0.43)	SLC6A2SLC6A4SLC6A3DAGLACACNA1G
	SCHEMBL2116168	0.75	DAGLA (0.43)	SLC6A2SLC6A4SLC6A3DAGLAALDH1A1
	SCHEMBL1706233	0.74	LOXL2 (0.44)	SLC6A2SLC6A4SLC6A3DAGLACACNA1G
	SCHEMBL1975554	0.74	KLKB1 (0.56)	SLC6A2SLC6A4SLC6A3DAGLAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.