SCHEMBL5220877

SCHEMBL5220877

Cc1nc2n(c1C=O)CC(Cl)CC2=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5222472 0.69 DRD2 (0.34)
SCHEMBL5619909 0.62
SCHEMBL5216737 0.55 LMNA (0.30)
SCHEMBL28055832 0.51
SCHEMBL6209906 0.50 ALOX12 (0.54)
SCHEMBL4591323 0.49 DRD2 (0.39)
SCHEMBL27848333 0.48 KDM4E (0.42)
SCHEMBL9798631 0.46 EGFR (0.34)
SCHEMBL1697663 0.46 KCNJ1 (0.37)
SCHEMBL24512545 0.45 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189736-B2 Prodrugs of imidazopyridine derivatives ALTANA PHARMA AG (DE) 2007-03-13 US disclosed
EP-1303519-B1 TRICYCLIC IMIDAZOPYRIDINES ALTANA PHARMA AG (DE) 2007-03-07 EP disclosed
US-7141567-B2 Polysubstituted imidazopyridines as gastric secretion inhibitors ALTANA PHARMA AG (DE) 2006-11-28 US disclosed
EP-1313739-B1 ALKYLATED IMIDAZOPYRIDINE DERIVATIVES ALTANA PHARMA AG (DE) 2006-07-05 EP disclosed
EP-1286993-B1 IMIDAZOPYRIDIN-8-ONES ALTANA PHARMA AG (DE) 2006-06-07 EP disclosed
EP-1313740-B1 PRODRUGS OF IMIDAZOPYRIDINE DERIVATIVES ALTANA PHARMA AG (DE) 2005-11-30 EP disclosed
US-6916825-B2 Alkylated imidazopyridine derivatives ALTANA PHARMA AG (DE) 2005-07-12 US disclosed
US-6869949-B2 Polysubstituted imidazopyridines as gastric secretion inhibitors ALTANA PHARMA AG (DE) 2005-03-22 US disclosed
US-20040214852-A1 Polysubstituted imidazopyridines ALTANA PHARMA AG (DE) 2004-10-28 US disclosed
US-20040198764-A1 Prodrugs of imidazopyridine derivatives SENN-BILFINGER JORG (DE) 2004-10-07 US disclosed
EP-1313739-A1 ALKYLATED IMIDAZOPYRIDINE DERIVATIVES ALTANA Pharma AG (DE) 2003-05-28 EP disclosed
EP-1313740-A1 PRODRUGS OF IMIDAZOPYRIDINE DERIVATIVES ALTANA Pharma AG (DE) 2003-05-28 EP disclosed
EP-1303519-A1 TRICYCLIC IMIDAZOPYRIDINES ALTANA Pharma AG (DE) 2003-04-23 EP disclosed
WO-2001072748-A9 IMIDAZOPYRIDIN-8-ONES ALTANA PHARMA AG (DE) 2003-04-10 WO disclosed
EP-1286993-A1 IMIDAZOPYRIDIN-8-ONES ALTANA Pharma AG (DE) 2003-03-05 EP disclosed
WO-2002034749-A1 POLYSUBSTITUTED IMIDAZOPYRIDINES AS GASTRIC SECRETION INHIBITORS ALTANA PHARMA AG (DE) 2002-05-02 WO disclosed
WO-2001072757-A1 TRICYCLIC IMIDAZOPYRIDINES ALTANA PHARMA AG (DE) 2001-10-04 WO disclosed
WO-2001072754-A1 ALKYLATED IMIDAZOPYRIDINE DERIVATIVES ALTANA PHARMA AG (DE) 2001-10-04 WO disclosed
WO-2001072756-A1 PRODRUGS OF IMIDAZOPYRIDINE DERIVATIVES ALTANA PHARMA AG (DE) 2001-10-04 WO disclosed
WO-2001072748-A1 IMIDAZOPYRIDIN-8-ONES ALTANA PHARMA AG (DE) 2001-10-04 WO disclosed