Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222472 | 0.78 | DRD2 (0.34) | DRD2HTR2AHTR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13525311 | 0.77 | DRD2 (0.51) | DRD2HTR2AHTR1AKDM4ECYP1A2 | |
| SCHEMBL14278538 | 0.72 | ATM (0.46) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL7979271 | 0.72 | L3MBTL1 (0.41) | DRD2HTR2AHTR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4580083 | 0.68 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL13360488 | 0.67 | POLB (0.48) | SMN1; SMN2ALDH1A1HSD17B10ALOX15POLB | |
| SCHEMBL2616364 | 0.67 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL8810859 | 0.66 | GRM2 (0.49) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL19006734 | 0.65 | POLB (0.52) | SMN1; SMN2ALDH1A1HSD17B10ALOX15POLB | |
| SCHEMBL5619238 | 0.63 | L3MBTL1 (0.37) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899341-A1 | SPIRO-IMIDAZNAPHTHYRIDINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | Nycomed GmbH (DE) | 2008-03-19 | — | — | EP | disclosed |
| US-7314935-B2 | Tricyclic n-acyl compounds | ALTANA PHARMA AG (DE) | 2008-01-01 | — | — | US | disclosed |
| EP-1286999-B1 | PYRANO[2,3-c]IMIDAZO[1,2-a]PYRIDINE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | NYCOMED GMBH (DE) | 2007-12-19 | — | — | EP | disclosed |
| US-7189736-B2 | Prodrugs of imidazopyridine derivatives | ALTANA PHARMA AG (DE) | 2007-03-13 | — | — | US | disclosed |
| EP-1303519-B1 | TRICYCLIC IMIDAZOPYRIDINES | ALTANA PHARMA AG (DE) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006134112-A1 | SPIRO-IMIDAZNAPHTHYRIDINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | NYCOMED GMBH (DE) | 2006-12-21 | — | — | WO | disclosed |
| US-7141567-B2 | Polysubstituted imidazopyridines as gastric secretion inhibitors | ALTANA PHARMA AG (DE) | 2006-11-28 | — | — | US | disclosed |
| US-20060194972-A1 | Process for the production of imidazopyridin-8-ones | ALTANA PHARMA AG (DE) | 2006-08-31 | — | — | US | disclosed |
| EP-1414821-B1 | TRICYCLIC EPOXIDES | ALTANA PHARMA AG (DE) | 2006-08-16 | — | — | EP | disclosed |
| EP-1313739-B1 | ALKYLATED IMIDAZOPYRIDINE DERIVATIVES | ALTANA PHARMA AG (DE) | 2006-07-05 | — | — | EP | disclosed |
| EP-1303519-A1 | TRICYCLIC IMIDAZOPYRIDINES | ALTANA Pharma AG (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2001072748-A9 | IMIDAZOPYRIDIN-8-ONES | ALTANA PHARMA AG (DE) | 2003-04-10 | — | — | WO | disclosed |
| EP-1286993-A1 | IMIDAZOPYRIDIN-8-ONES | ALTANA Pharma AG (DE) | 2003-03-05 | — | — | EP | disclosed |
| EP-1286999-A1 | PYRANO[2,3-c]IMIDAZO[1,2-a]PYRIDINE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | ALTANA Pharma AG (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2003014119-A1 | TRICYCLIC EPOXIDES | ALTANA PHARMA AG (DE) | 2003-02-20 | — | — | WO | disclosed |
| WO-2001072757-A1 | TRICYCLIC IMIDAZOPYRIDINES | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001072755-A1 | PYRANO[2,3-C]IMIDAZO[-1,2-A]PYRIDINE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001072756-A1 | PRODRUGS OF IMIDAZOPYRIDINE DERIVATIVES | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001072748-A1 | IMIDAZOPYRIDIN-8-ONES | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001072754-A1 | ALKYLATED IMIDAZOPYRIDINE DERIVATIVES | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194972-A1 | Process for the production of imidazopyridin-8-ones | NISCH, NDUFS8, BRSK1 | DRD2 4136/4885HTR2A 2608/4885HTR1A 2835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.