SCHEMBL5222472

SCHEMBL5222472

Cc1nc2n(c1C=O)CCCC2=O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 3/20 0.34
HTR2A P28223 3/20 0.34
HTR1A P08908 2/20 0.34
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4591323 0.78 DRD2 (0.39) DRD2HTR2AHTR1AALDH1A1SMN1; SMN2
SCHEMBL5220877 0.69
SCHEMBL13525311 0.68 DRD2 (0.51) DRD2HTR2AHTR1A
SCHEMBL7979271 0.67 L3MBTL1 (0.41) DRD2HTR2AHTR1AALDH1A1SMN1; SMN2
SCHEMBL4580083 0.63 SMN1; SMN2 (0.32) ALDH1A1SMN1; SMN2
SCHEMBL8810859 0.61 GRM2 (0.49) ALDH1A1SMN1; SMN2
SCHEMBL9845979 0.61 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2
SCHEMBL5619238 0.58 L3MBTL1 (0.37) ALDH1A1SMN1; SMN2
SCHEMBL2616364 0.58 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2
SCHEMBL18367145 0.56 BRD4 (0.41) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189736-B2 Prodrugs of imidazopyridine derivatives ALTANA PHARMA AG (DE) 2007-03-13 US disclosed
EP-1303519-B1 TRICYCLIC IMIDAZOPYRIDINES ALTANA PHARMA AG (DE) 2007-03-07 EP disclosed
US-7141567-B2 Polysubstituted imidazopyridines as gastric secretion inhibitors ALTANA PHARMA AG (DE) 2006-11-28 US disclosed
EP-1313739-B1 ALKYLATED IMIDAZOPYRIDINE DERIVATIVES ALTANA PHARMA AG (DE) 2006-07-05 EP disclosed
EP-1286993-B1 IMIDAZOPYRIDIN-8-ONES ALTANA PHARMA AG (DE) 2006-06-07 EP disclosed
EP-1313740-B1 PRODRUGS OF IMIDAZOPYRIDINE DERIVATIVES ALTANA PHARMA AG (DE) 2005-11-30 EP disclosed
US-6916825-B2 Alkylated imidazopyridine derivatives ALTANA PHARMA AG (DE) 2005-07-12 US disclosed
US-6869949-B2 Polysubstituted imidazopyridines as gastric secretion inhibitors ALTANA PHARMA AG (DE) 2005-03-22 US disclosed
US-20040214852-A1 Polysubstituted imidazopyridines ALTANA PHARMA AG (DE) 2004-10-28 US disclosed
US-20040198764-A1 Prodrugs of imidazopyridine derivatives SENN-BILFINGER JORG (DE) 2004-10-07 US disclosed
EP-1313739-A1 ALKYLATED IMIDAZOPYRIDINE DERIVATIVES ALTANA Pharma AG (DE) 2003-05-28 EP disclosed
EP-1313740-A1 PRODRUGS OF IMIDAZOPYRIDINE DERIVATIVES ALTANA Pharma AG (DE) 2003-05-28 EP disclosed
EP-1303519-A1 TRICYCLIC IMIDAZOPYRIDINES ALTANA Pharma AG (DE) 2003-04-23 EP disclosed
WO-2001072748-A9 IMIDAZOPYRIDIN-8-ONES ALTANA PHARMA AG (DE) 2003-04-10 WO disclosed
EP-1286993-A1 IMIDAZOPYRIDIN-8-ONES ALTANA Pharma AG (DE) 2003-03-05 EP disclosed
WO-2002034749-A1 POLYSUBSTITUTED IMIDAZOPYRIDINES AS GASTRIC SECRETION INHIBITORS ALTANA PHARMA AG (DE) 2002-05-02 WO disclosed
WO-2001072757-A1 TRICYCLIC IMIDAZOPYRIDINES ALTANA PHARMA AG (DE) 2001-10-04 WO disclosed
WO-2001072754-A1 ALKYLATED IMIDAZOPYRIDINE DERIVATIVES ALTANA PHARMA AG (DE) 2001-10-04 WO disclosed
WO-2001072756-A1 PRODRUGS OF IMIDAZOPYRIDINE DERIVATIVES ALTANA PHARMA AG (DE) 2001-10-04 WO disclosed
WO-2001072748-A1 IMIDAZOPYRIDIN-8-ONES ALTANA PHARMA AG (DE) 2001-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040198764-A1 Prodrugs of imidazopyridine derivatives SI, CYP2E1, UGT1A1 DRD2 3277/4885HTR2A 2589/4885HTR1A 1400/4885
US-20040214852-A1 Polysubstituted imidazopyridines GIPR, VIP, SLC10A2 DRD2 1363/4885HTR2A 898/4885HTR1A 668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.