SCHEMBL522214

SCHEMBL522214

Nc1[c]ccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 2/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
CYP3A4 P08684 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ADORA2A P29274 3/20 0.34
ADORA1 P30542 3/20 0.34
POLB P06746 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
ADORA2B P29275 1/20 0.34
TDO2 P48775 3/20 0.34
SMARCA2 P51531 1/20 0.34
SMARCA4 P51532 1/20 0.34
PBRM1 Q86U86 1/20 0.34
BACE1 P56817 1/20 0.33
DHFR P00374 1/20 0.33
HEXA P06865 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891578 0.77 LMNA (0.36) HSD17B10ALDH1A1LMNAMAPTHTT
SCHEMBL999508 0.75 LMNA (0.34) HSD17B10ALDH1A1LMNAMAPTHTT
SCHEMBL6250246 0.75 LMNA (0.34) HSD17B10ALDH1A1LMNAMAPTHTT
SCHEMBL6829533 0.75 CYP2A6 (0.36) HSD17B10ALDH1A1LMNAMAPTHTT
SCHEMBL8497176 0.75 BACE1 (0.43) HSD17B10ALDH1A1LMNAMAPTHTT
SCHEMBL7393282 0.74 ALDH1A1 (0.50) HSD17B10ALDH1A1LMNACYP3A4TAAR1
SCHEMBL8510133 0.71 ALDH1A1 (0.37) HSD17B10ALDH1A1LMNAMAPTHTT
SCHEMBL16150176 0.71 GCGR (0.34) LMNAMAPTHTTADORA2AADORA1
SCHEMBL8477966 0.71 DHFR (0.38) LMNAMAPTHTTADORA2AADORA1
SCHEMBL8595494 0.71 PLK1 (0.35) LMNAMAPTHTTADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115710280-B Dithienophenazine receptor-based compounds, synthesis method and application thereof 黑龙江大学 2024-04-02 CN claimed
CN-115710280-B Dithienophenazine receptor-based compounds, synthesis method and application thereof 黑龙江大学 2024-04-02 CN disclosed
US-20140234763-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2014-08-21 US disclosed
EP-2535774-B1 Image bearing drum, image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2014-07-30 EP disclosed
US-20140030644-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-01-30 US disclosed
US-8617778-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-12-31 US disclosed
US-8535862-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-09-17 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
EP-2138899-B1 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH CO LTD (JP) 2013-02-27 EP disclosed
US-8343698-B2 Photoreceptor, method of manufacturing same, image formation method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-01-01 US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 US disclosed
US-20080145778-A1 IMAGE FORMING APPARATUS SOCKET MOBILE, INC. FKA SOCKET COMMUNICATIONS, INC. 2008-06-19 US disclosed
US-20080031653-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-02-07 US disclosed
EP-1862858-A1 Image bearing member, and process cartridge and image forming apparatus using the same Ricoh Company, Ltd. (JP) 2007-12-05 EP disclosed
US-20070212626-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070196749-A1 IMAGE BEARING MEMBER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS RICOH COMPANY, LIMITED (JP) 2007-08-23 US disclosed
US-20070196750-A1 IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LIMITED. (JP) 2007-08-23 US disclosed
US-20060240346-A1 Image bearing member, and image forming apparatus and process cartridge using the same RICOH COMPANY LIMITED (JP) 2006-10-26 US disclosed
EP-1712956-A2 Image bearing member, and image forming apparatus and process cartridge using the same Ricoh Company, Ltd. (JP) 2006-10-18 EP disclosed
US-20060197823-A1 Image forming apparatus RICOH COMPANY, LTD. (JP) 2006-09-07 US disclosed