Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737037 | 0.81 | SMN1; SMN2 (0.37) | LMNAMAPTHTTSMN1; SMN2HPGD | |
| SCHEMBL2395150 | 0.81 | PLK1 (0.38) | PLK1LMNAMAPTHTTBACE1 | |
| SCHEMBL12817155 | 0.81 | ADORA3 (0.30) | ADORA3ADORA2AADORA1BACE1SMN1; SMN2 | |
| SCHEMBL7152266 | 0.77 | PDE4B (0.36) | LMNAMAPTADORA1PDE4BSMN1; SMN2 | |
| SCHEMBL3539990 | 0.77 | ALDH1A1 (0.35) | ADORA3ADORA2AADORA1BACE1SMN1; SMN2 | |
| SCHEMBL23294 | 0.75 | CHRNB2 (0.32) | — | |
| SCHEMBL6829533 | 0.75 | CYP2A6 (0.36) | LMNAMAPTHTTBACE1PDE4B | |
| SCHEMBL6131760 | 0.74 | PTGS2 (0.35) | LMNAMAPTHTTSMN1; SMN2HPGD | |
| SCHEMBL891578 | 0.72 | LMNA (0.36) | LMNAMAPTHTTBACE1PDE4B | |
| SCHEMBL522214 | 0.71 | HSD17B10 (0.41) | LMNAMAPTHTTADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245852-B1 | PROCESS FOR PREPARING LIQUID TRIARYL THIOPHOSPHATE MIXTURES | AKZO N.V. (NL) | 1993-02-03 | — | — | EP | claimed |
| US-9650586-B2 | Redox couple-based mitigation of fluid-flow-driven electrochemical surface degradation | THE BOEING COMPANY (US) | 2017-05-16 | — | — | US | disclosed |
| EP-3118288-A1 | REDOX COUPLE-BASED MITIGATION OF ELECTROCHEMICAL SURFACE DEGRADATION IN PHOSPHATE-ESTER BASED HYDRAULIC SYSTEMS | The Boeing Company (US) | 2017-01-18 | — | — | EP | disclosed |
| US-9546338-B2 | Redox couple-based mitigation of fluid-flow-driven electrochemical surface degradation | THE BOEING COMPANY (US) | 2017-01-17 | — | — | US | disclosed |
| EP-2829595-B1 | Redox couple-based mitigation of fluid-flow-driven electrochemical surface degradation in phosphate-ester based hydraulic systems | BOEING CO (US) | 2016-09-14 | — | — | EP | disclosed |
| US-20160152919-A1 | REDOX COUPLE-BASED MITIGATION OF FLUID-FLOW-DRIVEN ELECTROCHEMICAL SURFACE DEGRADATION | THE BOEING COMPANY | 2016-06-02 | — | — | US | disclosed |
| US-20150099677-A1 | REDOX COUPLE-BASED MITIGATION OF FLUID-FLOW-DRIVEN ELECTROCHEMICAL SURFACE DEGRADATION | THE BOEING COMPANY (US) | 2015-04-09 | — | — | US | disclosed |
| EP-2829595-A1 | Redox couple-based mitigation of fluid-flow-driven electrochemical surface degradation in phosphate-ester based hydraulic systems | The Boeing Company (US) | 2015-01-28 | — | — | EP | disclosed |
| EP-0573082-B1 | Triaryl phosphate ester composition and process for its preparation | FMC CORP (US) | 1998-01-14 | — | — | EP | disclosed |
| US-5206404-A | Purifying by passing through thin film evaporators; oxidation, wear, heat, hydroytic stability | FMC CORPORATION (US) | 1993-04-27 | — | — | US | disclosed |