Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456908 | 0.87 | MAOA (0.34) | CYP2A6CYP2B6LMNAMAPTHTT | |
| SCHEMBL8210178 | 0.82 | HDAC4 (0.44) | CYP2A6CYP2B6MAOBAKT2AKT1 | |
| SCHEMBL11269403 | 0.81 | PDCD1 (0.42) | CYP2A6CYP2B6LMNAAKT2AKT1 | |
| SCHEMBL439377 | 0.81 | BRD4 (0.37) | CYP2A6CYP2B6LMNAMAPTHTT | |
| SCHEMBL11019765 | 0.80 | SENP1 (0.45) | ESR2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7461959 | 0.78 | CYP2A6 (0.35) | CYP2A6CYP2B6AKT2AKT1ESR2 | |
| SCHEMBL7469723 | 0.78 | CYP2A6 (0.40) | CYP2A6CYP2B6LMNAMAPTAKT2 | |
| SCHEMBL17180554 | 0.78 | TAAR1 (0.38) | LMNAMAPTHTTAKT2BRD4 | |
| SCHEMBL8131053 | 0.78 | PTGS1 (0.37) | CYP2A6LMNAMAPTHTTAKT2 | |
| SCHEMBL16344216 | 0.77 | RAB9A (0.37) | MAOBMAPTKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066138-A1 | FLAME RETARDANT THERMOPLASTIC POLYMER COMPOSITIONS | DOW CORNING CORPORATION (US) | 2015-05-07 | — | — | WO | disclosed |
| US-8937195-B2 | Method for producing the transition metal complex, catalyst for trimerization, method for producing 1-hexene, method for producing the substituted cyclopentadiene compound (1) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-01-20 | — | — | US | disclosed |
| EP-2691406-A1 | METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (1) | Sumitomo Chemical Company, Limited (JP) | 2014-02-05 | — | — | EP | disclosed |
| US-20140018564-A1 | METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (1) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-16 | — | — | US | disclosed |
| WO-2012133935-A1 | METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (3) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012133924-A1 | METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (1) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | WO | disclosed |
| US-20040166133-A1 | Method of making a mascara composition comprising polyamide polymer and at least one solid substance having a melting point of 45oC or greater | L'OREAL | 2004-08-26 | — | — | US | disclosed |
| US-20030147837-A1 | Cosmetic composition comprising hetero polymers and a solid substance and method of using same | CAVAZZUTI ROBERTO (FR) | 2003-08-07 | — | — | US | disclosed |
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040166133-A1 | Method of making a mascara composition comprising polyamide polymer and at least one solid substance having a melting point of 45oC or greater | MATR3, CUTA, PARG | CYP2A6 2772/4885CYP2B6 3258/4885MAOB 2624/4885 |
| US-20030147837-A1 | Cosmetic composition comprising hetero polymers and a solid substance and method of using same | CUTA, FABP4, PLIN3 | CYP2A6 764/4885CYP2B6 463/4885MAOB 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.