Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891578 | 0.77 | LMNA (0.36) | LMNAMAPTHTTBACE1HDAC4 | |
| SCHEMBL6250246 | 0.75 | LMNA (0.34) | LMNAMAPTHTTBACE1HDAC4 | |
| SCHEMBL6829533 | 0.75 | CYP2A6 (0.36) | LMNAMAPTHTTBACE1HDAC4 | |
| SCHEMBL8497176 | 0.75 | BACE1 (0.43) | LMNAMAPTHTTBACE1HDAC4 | |
| SCHEMBL522214 | 0.75 | HSD17B10 (0.41) | LMNAMAPTHTTBACE1ALDH1A1 | |
| SCHEMBL2395150 | 0.75 | PLK1 (0.38) | LMNAMAPTHTTBACE1ALDH1A1 | |
| SCHEMBL8510133 | 0.71 | ALDH1A1 (0.37) | LMNAMAPTHTTBACE1HDAC4 | |
| SCHEMBL8477966 | 0.71 | DHFR (0.38) | LMNAMAPTHTTBACE1 | |
| SCHEMBL7468941 | 0.71 | PDE4B (0.40) | LMNAMAPTHTTBACE1ALDH1A1 | |
| SCHEMBL3850051 | 0.71 | CYP2A6 (0.33) | LMNAMAPTHTTBACE1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299250-B2 | Chiral tridentate compounds, corresponding organometal complexes, method for preparing same and use of said compounds and complexes as ligands in asymmetrical catalysis | ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES (FR) | 2012-10-30 | — | — | US | claimed |
| EP-2200986-B1 | Chiral tridentate compounds, corresponding organometal complexes, method for preparing same and use of said compounds and complexes as ligands in asymmetrical catalysis | ENSCR (FR) | 2012-08-08 | — | — | EP | claimed |
| JP-2011500646-A | — | — | 2011-01-06 | — | — | JP | claimed |
| US-20100267956-A1 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | CNRS (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE) (FR) | 2010-10-21 | — | — | US | claimed |
| EP-2200986-A2 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | Ecole Nationale Superieure De Chimie De Rennes (FR) | 2010-06-30 | — | — | EP | claimed |
| WO-2009050284-A2 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2009-04-23 | — | — | WO | claimed |
| US-8299250-B2 | Chiral tridentate compounds, corresponding organometal complexes, method for preparing same and use of said compounds and complexes as ligands in asymmetrical catalysis | ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES (FR) | 2012-10-30 | — | — | US | disclosed |
| EP-2200986-B1 | Chiral tridentate compounds, corresponding organometal complexes, method for preparing same and use of said compounds and complexes as ligands in asymmetrical catalysis | ENSCR (FR) | 2012-08-08 | — | — | EP | disclosed |
| US-20100267956-A1 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | CNRS (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE) (FR) | 2010-10-21 | — | — | US | disclosed |
| EP-2200986-A2 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | Ecole Nationale Superieure De Chimie De Rennes (FR) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009050284-A2 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267956-A1 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | AOC1, C1R, AOC3 | LMNA 4242/4885MAPT 4441/4885HTT 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.