Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224505 | 1.00 | CTSD (0.34) | CTSDBACE1BACE2FDPSCYP3A4 | |
| SCHEMBL5223660 | 0.82 | RAB9A (0.38) | CTSDBACE1BACE2 | |
| SCHEMBL5223654 | 0.82 | RAB9A (0.38) | CTSDBACE1BACE2 | |
| SCHEMBL5226207 | 0.80 | CTSD (0.38) | CTSDBACE1BACE2 | |
| SCHEMBL5226201 | 0.80 | CTSD (0.38) | CTSDBACE1BACE2 | |
| SCHEMBL5218367 | 0.78 | MEN1 (0.36) | CTSDBACE1BACE2CYP3A4 | |
| SCHEMBL5218356 | 0.78 | MEN1 (0.36) | CTSDBACE1BACE2CYP3A4 | |
| SCHEMBL5379994 | 0.77 | FDPS (0.35) | CTSDBACE1BACE2FDPSACACB | |
| Hydrochloric Acid SCHEMBL5219204 | 0.76 | FDPS (0.35) | CTSDBACE1BACE2FDPSACACB | |
| SCHEMBL5223196 | 0.76 | CTSD (0.38) | CTSDBACE1BACE2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |