Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224678 | 1.00 | PTGS2 (0.34) | PTGS2ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL5219097 | 0.97 | PTGS2 (0.33) | PTGS2ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL5219089 | 0.97 | PTGS2 (0.33) | PTGS2ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL5219078 | 0.97 | PTGS2 (0.33) | PTGS2ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL5224667 | 0.89 | PIK3C3 (0.37) | PTGS2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5224665 | 0.89 | PIK3C3 (0.37) | PTGS2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5219084 | 0.85 | CTSD (0.36) | PTGS2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5226788 | 0.82 | OPRK1 (0.35) | — | |
| SCHEMBL5223226 | 0.79 | KDM4E (0.38) | ALDH1A1HPGDHSD17B10KDM4ENPC1 | |
| SCHEMBL5218534 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |