Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 5/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.57 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222119 | 0.77 | KMT2A (0.44) | ABL1ABCB1BCRMAPTKDM4E | |
| SCHEMBL5226722 | 0.75 | KMT2A (0.43) | ABL1ABCB1BCRMAPTKDM4E | |
| SCHEMBL5227004 | 0.74 | NPC1 (0.62) | ABL1ABCB1BCRMAPTKDM4E | |
| SCHEMBL5227509 | 0.74 | MAPT (0.55) | ABL1ABCB1BCRMAPTKDM4E | |
| SCHEMBL5224164 | 0.74 | ADORA1 (0.49) | ABL1ABCB1BCRMAPTKDM4E | |
| SCHEMBL5223497 | 0.73 | SMN1; SMN2 (0.54) | MAPTKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL5225103 | 0.73 | PTGS2 (0.48) | MAPTKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL1752996 | 0.73 | MAPK14 (1.00) | MAPK11MAPK14CSNK1DNPC1PKM | |
| SCHEMBL5225376 | 0.73 | ALOX5 (0.51) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL5227512 | 0.73 | KMT2A (0.48) | ABL1ABCB1BCRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300399-B1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2007-08-22 | — | — | EP | disclosed |
| US-6664256-B1 | Interleukin- 1 beta inhibitors | KOWA CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| EP-1300399-A1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |