Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223978 | 0.86 | GAA (0.50) | PTGS2KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL5227512 | 0.79 | KMT2A (0.48) | PTGS2KDM4ETP53RAB9ABACE1 | |
| SCHEMBL5225056 | 0.73 | MAPK11 (0.57) | PTGS2KDM4EALDH1A1RAB9AHSD17B10 | |
| SCHEMBL6315377 | 0.72 | MALT1 (0.44) | ALOX5PTGS2ALDH1A1KMT2A | |
| SCHEMBL5223497 | 0.72 | SMN1; SMN2 (0.54) | KDM4EALDH1A1BACE1SMN1; SMN2HPGD | |
| SCHEMBL7756777 | 0.72 | OPRD1 (0.52) | ALOX5PTGS2KDM4EALDH1A1TP53 | |
| SCHEMBL5223691 | 0.71 | ALDH1A1 (0.46) | PTGS2KDM4EALDH1A1TP53RAB9A | |
| SCHEMBL6308862 | 0.69 | ALOX5 (0.51) | ALOX5PTGS2ALDH1A1KMT2A | |
| SCHEMBL9520508 | 0.68 | ALOX5 (0.83) | ALOX5PTGS2 | |
| SCHEMBL7761536 | 0.68 | OPRD1 (0.48) | ALOX5PTGS2KDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300399-B1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2007-08-22 | — | — | EP | disclosed |
| US-6664256-B1 | Interleukin- 1 beta inhibitors | KOWA CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| EP-1300399-A1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |