Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5443979 | 0.86 | BCL2 (0.48) | LTA4HPTPN1L3MBTL1ALOX5TSPO | |
| SCHEMBL5226181 | 0.81 | L3MBTL1 (0.52) | LTA4HPTPN1L3MBTL1ALOX5TSPO | |
| SCHEMBL14375790 | 0.79 | POLB (0.50) | ALDH1A1 | |
| SCHEMBL22252000 | 0.74 | KEAP1 (0.76) | L3MBTL1ALDH1A1NR1H4CNR2 | |
| SCHEMBL483 | 0.73 | ALOX5 (0.56) | LTA4HL3MBTL1ALOX5TSPOPTGS1 | |
| SCHEMBL5226093 | 0.72 | MEN1 (0.43) | LTA4HL3MBTL1ALOX5TSPOPTGS1 | |
| SCHEMBL1690682 | 0.72 | RAB9A (0.71) | LTA4HALDH1A1 | |
| SCHEMBL4673505 | 0.71 | CA12 (0.48) | ALOX5ALDH1A1CNR2 | |
| SCHEMBL5223394 | 0.71 | L3MBTL1 (0.41) | LTA4HL3MBTL1ALOX5TSPOPTGS1 | |
| SCHEMBL14020494 | 0.70 | CA2 (0.58) | L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778654-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | Crystalgenomics, Inc. (KR) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006006832-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | CRYSTALGENOMICS, INC. (KR) | 2006-01-19 | — | — | WO | disclosed |