Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | STK17B | O94768 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226252 | 0.99 | PIK3CD (0.32) | PIK3CDSTK17BPDGFRAPDGFRB | |
| SCHEMBL5228680 | 0.94 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL5230676 | 0.93 | PIK3CD (0.36) | PIK3CD | |
| SCHEMBL5226593 | 0.91 | PIK3CD (0.31) | PIK3CD | |
| SCHEMBL5227163 | 0.89 | POLB (0.31) | PIK3CD | |
| SCHEMBL5227538 | 0.88 | MPO (0.36) | — | |
| SCHEMBL5224808 | 0.87 | MPO (0.37) | — | |
| SCHEMBL5224156 | 0.86 | ADRA1D (0.30) | — | |
| SCHEMBL5225473 | 0.76 | METAP2 (0.38) | — | |
| SCHEMBL5213315 | 0.74 | PDGFRA (0.33) | PIK3CDPDGFRAKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636212-B1 | CYCLOALKYLSULFANYL SUBSTITUTED BENZO¬B|THIOPHENES AS THERAPEUTIC AGENTS | WARNER LAMBERT CO (US) | 2007-06-27 | — | — | EP | claimed |