Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437264 | 0.83 | ALDH1A1 (0.42) | ALDH1A1ALDH1A3TSHRKDM4EPTGS2 | |
| SCHEMBL9391621 | 0.79 | ALDH1A1 (0.40) | TYRALDH1A1ALDH1A3TSHRKDM4E | |
| SCHEMBL29214423 | 0.79 | ALDH1A3 (0.47) | TYRALDH1A1ALDH1A3TSHRKDM4E | |
| SCHEMBL13269290 | 0.79 | ALDH1A1 (0.52) | TYRALDH1A1ALDH1A3TSHRKDM4E | |
| SCHEMBL16542178 | 0.76 | TYR (0.36) | TYRALDH1A1ALDH1A3TSHRKDM4E | |
| SCHEMBL26690356 | 0.76 | ALDH1A1 (0.58) | ALDH1A1ALDH1A3TSHRRAB9ATDP1 | |
| SCHEMBL13319265 | 0.76 | KDM4E (0.42) | ALDH1A1ALDH1A3TSHRKDM4EPTGS2 | |
| SCHEMBL4772939 | 0.75 | GABRA1 (0.58) | TYRALDH1A1TSHRKDM4EPTGS2 | |
| SCHEMBL27756844 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TSHRRAB9ATDP1FDPS | |
| SCHEMBL8061776 | 0.75 | CASP1 (0.43) | ALDH1A1TSHRKDM4ETDP1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |