Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5221674 | 0.88 | MAPT (0.41) | MAPTPKMTACR1HTR2CITGB3 | |
| SCHEMBL5227764 | 0.88 | MAPT (0.41) | MAPTPKMTACR1HTR2CITGB3 | |
| SCHEMBL5226602 | 0.88 | MAPT (0.41) | MAPTPKMTACR1HTR2CITGB3 | |
| SCHEMBL7367007 | 0.82 | ALDH1A1 (0.43) | HTR2CITGB3ITGA2B | |
| SCHEMBL8036361 | 0.79 | ITGB3 (0.45) | HTR2CITGB3ITGA2B | |
| SCHEMBL7397160 | 0.78 | ALDH1A1 (0.43) | HTR2CITGB3ITGA2B | |
| SCHEMBL4031368 | 0.75 | PREP (0.41) | HTR2C | |
| SCHEMBL13209102 | 0.73 | MAPT (0.54) | MAPTPKMSLC6A4 | |
| SCHEMBL3017415 | 0.73 | MAPT (0.54) | MAPTPKMSLC6A4 | |
| SCHEMBL14642003 | 0.73 | MAPT (0.54) | MAPTPKMSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789389-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006030984-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2006-03-23 | — | — | WO | disclosed |