Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036361 | 0.94 | ITGB3 (0.45) | ALDH1A1GAAHTR2CITGB3ITGA2B | |
| SCHEMBL7397160 | 0.94 | ALDH1A1 (0.43) | ALDH1A1GAAHTR2CITGB3ITGA2B | |
| SCHEMBL5225669 | 0.82 | MAPT (0.48) | HTR2CITGB3ITGA2B | |
| SCHEMBL5226602 | 0.81 | MAPT (0.41) | HTR2CITGB3ITGA2B | |
| SCHEMBL5227764 | 0.81 | MAPT (0.41) | HTR2CITGB3ITGA2B | |
| SCHEMBL5221674 | 0.81 | MAPT (0.41) | HTR2CITGB3ITGA2B | |
| SCHEMBL5222777 | 0.80 | TSHR (0.52) | ALDH1A1GAAHTR2CSMN1; SMN2TSHR | |
| SCHEMBL1001991 | 0.80 | TSHR (0.52) | ALDH1A1GAAHTR2CSMN1; SMN2TSHR | |
| SCHEMBL15626865 | 0.80 | TSHR (0.52) | ALDH1A1GAAHTR2CSMN1; SMN2TSHR | |
| SCHEMBL29017563 | 0.79 | TSHR (0.49) | ALDH1A1GAAHTR2CITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |
| EP-1080069-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999054284-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-28 | — | — | WO | disclosed |