Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMO | Q99835 | 4/20 | 0.53 |
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226797 | 0.89 | SMO (0.61) | L3MBTL1MAPTLMNASMOKMT2A | |
| SCHEMBL5224244 | 0.89 | SMO (0.49) | L3MBTL1MAPTLMNASMOCHKA | |
| SCHEMBL5228124 | 0.87 | SMO (0.43) | L3MBTL1MAPTLMNASMO | |
| SCHEMBL2761123 | 0.87 | SMO (0.50) | L3MBTL1MAPTLMNASMOCHKA | |
| SCHEMBL5226795 | 0.83 | SMO (0.42) | L3MBTL1MAPTLMNASMOCHKA | |
| SCHEMBL5227160 | 0.82 | SMO (0.41) | L3MBTL1MAPTLMNASMOCHKA | |
| SCHEMBL5228219 | 0.82 | SMO (0.47) | L3MBTL1MAPTLMNASMOHTR6 | |
| SCHEMBL5232263 | 0.82 | SMO (0.49) | L3MBTL1MAPTLMNASMOCHKA | |
| SCHEMBL5225265 | 0.81 | SMO (0.59) | L3MBTL1MAPTLMNASMOKMT2A | |
| SCHEMBL5737789 | 0.81 | SMO (0.44) | L3MBTL1MAPTLMNASMOHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |