Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP19 | O94966 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5418613 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTTSHR | |
| SCHEMBL30336156 | 0.76 | CYP11B1 (0.47) | NR3C2RIPK1 | |
| SCHEMBL4067526 | 0.76 | CYP11B1 (0.47) | NR3C2RIPK1 | |
| SCHEMBL18237838 | 0.76 | USP19 (0.41) | NR3C2ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL4790977 | 0.75 | CD74 (0.43) | NR3C2ALDH1A1KDM4EUSP19KMT2A | |
| SCHEMBL5227565 | 0.74 | KMT2A (0.50) | ALDH1A1MAPTTSHRKDM4EKMT2A | |
| SCHEMBL18937273 | 0.73 | USP19 (0.38) | NR3C2ALDH1A1MAPTKDM4EUSP19 | |
| SCHEMBL15204409 | 0.72 | RIPK1 (0.39) | NR3C2RIPK1 | |
| SCHEMBL15204408 | 0.72 | RIPK1 (0.39) | NR3C2RIPK1 | |
| SCHEMBL19859246 | 0.71 | CYP11B2 (0.47) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556387-B1 | SUBSTITUTED BENZOL E| 1,4| OXAZINO 3,2-G| ISOINDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-04-04 | — | — | EP | disclosed |
| EP-1556387-A1 | SUBSTITUTED BENZOL E] 1,4] OXAZINO 3,2-G] ISOINDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037830-A1 | SUBSTITUTED BENZOL[E] [1,4] OXAZINO[3,2-G] ISOINDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-05-06 | — | — | WO | disclosed |