SCHEMBL522652

SCHEMBL522652

OCc1cc(Cl)c(CO)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CBFB Q13951 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
IDO1 P14902 2/20 0.35
GRIA1 P42261 1/20 0.35
GRIA2 P42262 1/20 0.35
GRIA3 P42263 1/20 0.35
GRIA4 P48058 1/20 0.35
PDXK O00764 1/20 0.34
CYP3A4 P08684 3/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPT P10636 1/20 0.32
RECQL P46063 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9567411 0.94 HSD17B10 (0.41) CBFBALOX15ALOX12IDO1GRIA1
SCHEMBL1955558 0.87 GRIA1 (0.40) GRIA1GRIA2GRIA3GRIA4PDXK
SCHEMBL5385953 0.87 TSHR (0.55) ALOX15ALOX12IDO1PDXKCYP3A4
SCHEMBL6192193 0.84 GPR84 (0.37) CBFBCYP3A4CYP1A2CYP2C9MAPK1
SCHEMBL1315873 0.84 CBFB (0.31) CBFB
SCHEMBL31045274 0.84 GAA (0.57) CBFBALOX15CYP3A4MAPK1RECQL
SCHEMBL3824032 0.81 POLB (0.33) CBFBALOX15ALOX12MAPTHPGD
SCHEMBL14094903 0.81 SHBG (0.39) CBFBALOX15ALOX12CYP3A4PDE4A
SCHEMBL3617879 0.81 TSHR (0.55) ALOX15ALOX12IDO1PDXKCYP3A4
SCHEMBL13375339 0.81 GAA (0.46) CBFBALOX15CYP3A4MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018219574-A1 METHOD FOR PRODUCING FUNCTIONALIZED POLYESTERS HENKEL AG & CO. KGAA (DE) 2018-12-06 WO disclosed
EP-3409707-A1 METHOD FOR PRODUCING FUNCTIONALIZED POLYESTERS Henkel AG & Co. KGaA (DE) 2018-12-05 EP disclosed
US-9732168-B2 Method of preparing ethylene polymers by controlled high pressure polymerization BASF SE (DE) 2017-08-15 US disclosed
EP-2207851-B1 IN SITU MOISTURE GENERATION AND USE OF POLYFUNCTIONAL ALCOHOLS FOR CROSSLINKING OF SILANE-FUNCTIONALIZED RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-11-25 EP disclosed
EP-1891142-B1 OLIGO- AND POLY-CARBONATES TERMINATED WITH SILICON CONTAINING GROUPS AS SURFACE MODIFIERS CIBA HOLDING INC (CH) 2014-12-03 EP disclosed
US-20130150542-A1 Method Of Preparing Ethylene Polymers By Controlled High Pressure Polymerization BASF SE (DE) 2013-06-13 US disclosed
US-8460770-B2 In situ moisture generation and use of polyfunctional alcohols for crosslinking of silane-functionalized resins DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-11 US disclosed
EP-2415741-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2012-02-08 EP disclosed
EP-2415742-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR Sumitomo Chemical Company, Limited (JP) 2012-02-08 EP disclosed
US-20120029195-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-02 US disclosed
US-4148956-A TOUGH POLYESTERS WITH ACRYLONITRILE-STYRENE, MODIFIED WITH ACRYLATE, COPOLYMER ALKOR GMBH (DE) 1979-04-10 US disclosed
US-4108841-A FROM DIACIDS CONTAINING HETEROCYCLIC RINGS CIBA-GEIGY CORPORATION (US) 1978-08-22 US disclosed
US-4108834-A N,N-HETEROCYCLIC DIOLS CIBA-GEIGY CORPORATION (US) 1978-08-22 US disclosed
US-4101526-A Process for the manufacture of linear polyesters which contain phosphites and/or phosphates CIBA-GEIGY CORPORATION (US) 1978-07-18 US disclosed
US-4093639-A HEAT RESISTANCE CIBA-GEIGY CORPORATION (US) 1978-06-06 US disclosed
US-4031163-A CROSS LINKING SELF-EXTINGUISHING, THERMAL STABILITY DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-06-21 US disclosed
US-3998908-A PROCESS FOR THE MANUFACTURE OF STABILIZED POLYESTER-POLYCARBONATE COPOLYMERS CIBA-GEIGY CORPORATION (US) 1976-12-21 US disclosed
US-3997510-A CONTAINING BENZIMIDAZOLONE RADICAL CIBA-GEIGY CORPORATION (US) 1976-12-14 US disclosed
US-3994865-A MELT SPINNING CIBA-GEIGY CORPORATION (US) 1976-11-30 US disclosed
US-3975354-A Glass fiber-reinforced flame-resistant thermoplastic polyester moulding compositions containing poly(2,4,6-tribromostyrene) CIBA-GEIGY CORPORATION (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029195-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR ADH1A, ADH1C, ADH5 CBFB 1789/4885ALOX15 385/4885ALOX12 341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.