Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.45 |
| ▸ | EYA3 | Q99504 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227553 | 0.76 | SLC22A12 (0.53) | SLC22A12EYA3LMNAHTTMAPT | |
| SCHEMBL5227159 | 0.75 | EYA3 (0.66) | SLC22A12EYA3CYP2C9ESR1PTPN1 | |
| SCHEMBL5672687 | 0.73 | SLC22A12 (0.52) | SLC22A12EYA3LMNAHTTCYP3A4 | |
| SCHEMBL5962921 | 0.70 | CA2 (0.70) | LMNAHTTMAPTSMN1; SMN2POLB | |
| SCHEMBL10514760 | 0.67 | NPC1 (0.55) | CYP2C19CYP3A4MAPTCASP1SMN1; SMN2 | |
| SCHEMBL8624371 | 0.67 | HTT (0.63) | SLC22A12EYA3LMNAHTTCYP2C19 | |
| SCHEMBL11879835 | 0.66 | HSD17B3 (0.53) | LMNACYP2C19CYP3A4MAPTALOX15 | |
| SCHEMBL9471774 | 0.66 | HTT (0.58) | SLC22A12EYA3LMNAHTTCYP2C19 | |
| SCHEMBL4255166 | 0.66 | LMNA (0.58) | LMNAHTTCYP2C19CYP3A4MAPT | |
| SCHEMBL16547821 | 0.65 | SLC22A12 (0.51) | SLC22A12EYA3LMNAHTTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315710-A1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002016340-A1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-02-28 | — | — | WO | disclosed |