Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.42 |
| ▸ | F2 | P00734 | 13/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5907351 | 0.85 | F10 (0.44) | F10F2 | |
| SCHEMBL5228024 | 0.84 | HTR2C (0.42) | USP7HTR2CMCHR1 | |
| SCHEMBL5224144 | 0.80 | HTR2C (0.38) | F10F2HTR2CMCHR1 | |
| SCHEMBL2001554 | 0.80 | SMO (0.50) | F10F2HTR2CMCHR1 | |
| SCHEMBL7256608 | 0.79 | SSTR5 (0.42) | F10F2 | |
| SCHEMBL2001019 | 0.79 | CXCR3 (0.36) | F10F2USP7HTR2CMCHR1 | |
| SCHEMBL5227214 | 0.78 | SMO (0.52) | F10F2 | |
| SCHEMBL5225729 | 0.78 | F10 (0.38) | F10F2HTR2CMCHR1 | |
| SCHEMBL5228292 | 0.78 | SMO (0.37) | F10F2HTR2CMCHR1 | |
| SCHEMBL5228002 | 0.76 | TSHR (0.39) | HTR2CMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |