Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.38 |
| ▸ | F2 | P00734 | 9/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223624 | 0.85 | SMO (0.41) | PIK3CDSMO | |
| SCHEMBL5224153 | 0.85 | BRD4 (0.44) | PIK3CDSMO | |
| SCHEMBL5228017 | 0.84 | SMO (0.39) | ROCK2PIK3CDSMO | |
| SCHEMBL2001554 | 0.82 | SMO (0.50) | F10F2ROCK2HTR2CMCHR1 | |
| SCHEMBL5228292 | 0.82 | SMO (0.37) | F10F2ROCK2HTR2CMCHR1 | |
| SCHEMBL5224144 | 0.80 | HTR2C (0.38) | F10F2ROCK2HTR2CMCHR1 | |
| SCHEMBL5227619 | 0.78 | F10 (0.42) | F10F2HTR2CMCHR1 | |
| SCHEMBL5225124 | 0.78 | PIK3CD (0.42) | PIK3CD | |
| SCHEMBL5228024 | 0.77 | HTR2C (0.42) | ROCK2HTR2CMCHR1SMO | |
| SCHEMBL5227214 | 0.77 | SMO (0.52) | F10F2ROCK2SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |