Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | IDH1 | O75874 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230153 | 0.79 | LMNA (0.51) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL5230286 | 0.78 | IDH1 (0.48) | ALDH1A1MEN1KMT2ALMNAIDH1 | |
| SCHEMBL5228629 | 0.77 | IDH1 (0.51) | ALDH1A1MEN1KMT2ALMNAIDH1 | |
| SCHEMBL5237280 | 0.77 | CES1 (0.49) | ALDH1A1MEN1KMT2ALMNAIDH1 | |
| SCHEMBL5227161 | 0.72 | MEN1 (0.48) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL5231329 | 0.72 | IDH1 (0.48) | ALDH1A1MEN1KMT2AIDH1MAPT | |
| SCHEMBL5227591 | 0.70 | CDK1 (0.52) | ALDH1A1MEN1KMT2ALMNAIDH1 | |
| SCHEMBL5228023 | 0.69 | CA2 (0.49) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL15595336 | 0.68 | LMNA (0.68) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL9502563 | 0.68 | LMNA (0.56) | ALDH1A1MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |