Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.41 |
| ▸ | TST | Q16762 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234203 | 0.86 | ALDH1A1 (0.42) | DNMT1DNMT3AHSPD1PTPN2PTPN1 | |
| SCHEMBL5237280 | 0.83 | CES1 (0.49) | IDH1MEN1KMT2AALDH1A1 | |
| SCHEMBL5228023 | 0.82 | CA2 (0.49) | CA1CA2CA12CA9HPGD | |
| SCHEMBL5231082 | 0.81 | ALDH1A1 (0.43) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL5227591 | 0.81 | CDK1 (0.52) | IDH1MEN1KMT2AKITALDH1A1 | |
| SCHEMBL5228196 | 0.81 | CA12 (0.49) | CA2CA12CA9VCAM1MEN1 | |
| SCHEMBL5233848 | 0.79 | ACLY (0.39) | IDH1CA1CA2VCAM1MMP1 | |
| SCHEMBL5227928 | 0.78 | MEN1 (0.50) | CA1CA2HPGDMEN1KMT2A | |
| SCHEMBL5227161 | 0.78 | MEN1 (0.48) | HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL7997885 | 0.78 | L3MBTL1 (0.40) | HSD17B2MEN1KMT2AALDH1A1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043366-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |