Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 11/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1792492 | 0.87 | GRIN2B (0.53) | GRIN2BGRIN1NOS2MEN1ALDH1A1 | |
| SCHEMBL5269584 | 0.77 | LMNA (0.46) | GRIN2BGRIN1NOS2MEN1ALDH1A1 | |
| SCHEMBL5232108 | 0.77 | GRIN2D (0.48) | GRIN2BGRIN1MEN1ALDH1A1KMT2A | |
| SCHEMBL18795744 | 0.74 | LMNA (0.52) | MEN1ALDH1A1KMT2AGAAMGLL | |
| SCHEMBL45769 | 0.71 | GRIN2B (0.68) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL6313280 | 0.71 | GAA (0.41) | GRIN2BGRIN1NOS2ALDH1A1GRIN2D | |
| Hydrochloric Acid SCHEMBL4629266 | 0.69 | GRIN2B (0.72) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL7206541 | 0.69 | GRIN2B (0.65) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL8474170 | 0.69 | GRIN2B (0.49) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL1795009 | 0.68 | GRIN2B (0.43) | GRIN2BGRIN1NOS2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218337-B1 | SYNTHESIS OF 3,5,7|-1H-IMIDAZO 1,5-A|IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INST (US) | 2007-10-31 | — | — | EP | claimed |
| US-6545032-B1 | Combinatorial libraries | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2003-04-08 | — | — | US | claimed |
| US-20020193608-A1 | Synthesis of [3,5,7]--1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds | ELABDELLAOUI HASSAN M (US) | 2002-12-19 | — | — | US | claimed |
| EP-1218337-B1 | SYNTHESIS OF 3,5,7|-1H-IMIDAZO 1,5-A|IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INST (US) | 2007-10-31 | — | — | EP | disclosed |
| US-6809202-B2 | SYNTHETIC PEPTIDES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2004-10-26 | — | — | US | disclosed |
| US-20030120066-A1 | Synthetic peptides | NEFZI ADEL (US) | 2003-06-26 | — | — | US | disclosed |
| US-20020193608-A1 | Synthesis of [3,5,7]--1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds | ELABDELLAOUI HASSAN M (US) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193608-A1 | Synthesis of [3,5,7]--1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds | CYP3A7, CYP3A5, AADAC | GRIN2B 1084/4885GRIN1 190/4885NOS2 3828/4885 |
| US-20030120066-A1 | Synthetic peptides | VIP, NGLY1, GRPR | GRIN2B 2443/4885GRIN1 1052/4885NOS2 2959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.