Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 11/20 | 0.65 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.65 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.65 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.65 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.65 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.65 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.65 |
| ▸ | NOS2 | P35228 | 1/20 | 0.63 |
| ▸ | HTR3A | P46098 | 2/20 | 0.59 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.59 |
| ▸ | HTR3B | O95264 | 1/20 | 0.59 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.59 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45769 | 0.98 | GRIN2B (0.68) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| Hydrochloric Acid SCHEMBL4629266 | 0.95 | GRIN2B (0.72) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| Sulfuric Acid SCHEMBL4014387 | 0.87 | LMNA (0.65) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL1737052 | 0.85 | GRIN1 (0.62) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| Amphetamine SCHEMBL28092355 | 0.81 | TAAR1 (0.66) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL10425011 | 0.80 | GRIN2B (0.52) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL1736064 | 0.80 | TAAR1 (0.67) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL1736065 | 0.80 | TAAR1 (0.67) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL5670677 | 0.80 | LTA4H (0.55) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL20675953 | 0.79 | NOS2 (0.96) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004321-B1 | STABLE RADIOACTIVE MEDECINE | DAIICHI RADIOISOTOPE LAB (JP) | 2003-02-26 | — | — | EP | disclosed |
| EP-1004321-A1 | STABLE RADIOACTIVE MEDECINE | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2000-05-31 | — | — | EP | disclosed |