Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066546 | 0.83 | GRIN2D (0.56) | GAAGRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL1795008 | 0.83 | GRIN2D (0.56) | GAAGRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL5232108 | 0.81 | GRIN2D (0.48) | GAAGRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL5228993 | 0.74 | GAA (0.45) | GAAGRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL8471459 | 0.74 | GRIN2B (0.67) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL5231157 | 0.72 | GRIN2B (0.54) | GAAGRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL5267249 | 0.71 | GRIN2D (0.47) | GAAGRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL5228988 | 0.71 | GRIN2B (0.45) | GAAGRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL1792492 | 0.68 | GRIN2B (0.53) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL1795009 | 0.67 | GRIN2B (0.43) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861523-B2 | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2005-03-01 | — | — | US | claimed |
| US-6664282-B2 | For preparing and using libraries of compounds as well as individual compounds of the libraries; for screening compounds for combinatorial chemistry | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2003-12-16 | — | — | US | claimed |
| US-20030186320-A1 | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2003-10-02 | — | — | US | claimed |
| US-20050112693-A1 | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof | NEFZI ADEL (US) | 2005-05-26 | — | — | US | disclosed |
| US-6861523-B2 | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2005-03-01 | — | — | US | disclosed |
| US-6809202-B2 | SYNTHETIC PEPTIDES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2004-10-26 | — | — | US | disclosed |
| US-6664282-B2 | For preparing and using libraries of compounds as well as individual compounds of the libraries; for screening compounds for combinatorial chemistry | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2003-12-16 | — | — | US | disclosed |
| US-20030186320-A1 | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2003-10-02 | — | — | US | disclosed |
| US-6441172-B1 | DI- AND TRI-SUBSTITUTED-1,4-DIAZACYCLIC COMPOUNDS | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2002-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186320-A1 | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries | CDK15, CUL5, UTS2R | GAA 3667/4885GRIN1 1039/4885GRIN2B 1997/4885 |
| US-20050112693-A1 | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof | DHPS, DCK, DAZAP1 | GAA 989/4885GRIN1 843/4885GRIN2B 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.