Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231082 | 0.79 | ALDH1A1 (0.43) | ALDH3A1MEN1PKMKMT2AALDH1A1 | |
| SCHEMBL5227146 | 0.76 | LMNA (0.57) | SMN1; SMN2VCAM1MEN1PKMKMT2A | |
| SCHEMBL1939178 | 0.73 | CA1 (0.37) | VCAM1ALDH1A1TDP1CA1CA2 | |
| SCHEMBL5232126 | 0.73 | EPAS1 (0.40) | ALDH3A1EPAS1VCAM1MEN1PKM | |
| SCHEMBL5231215 | 0.72 | VCAM1 (0.40) | SMN1; SMN2VCAM1MEN1KMT2AALDH1A1 | |
| SCHEMBL15880676 | 0.71 | CA1 (0.53) | VCAM1ALDH1A1TDP1CA1CA2 | |
| SCHEMBL5227180 | 0.70 | LMNA (0.43) | EPAS1VCAM1CA1CA2LMNA | |
| SCHEMBL5227591 | 0.69 | CDK1 (0.52) | SMN1; SMN2MEN1PKMKMT2AALDH1A1 | |
| SCHEMBL7769090 | 0.69 | TSHR (0.41) | VCAM1ALDH1A1TDP1CA1CA2 | |
| SCHEMBL27633655 | 0.69 | PARP1 (0.41) | SMN1; SMN2VCAM1MEN1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |