SCHEMBL522960

SCHEMBL522960

OCc1c(F)c(F)c(F)c(CO)c1F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536295 0.96 POLB (0.32) POLB
SCHEMBL522934 0.93 POLB (0.33) POLB
SCHEMBL522840 0.89 SMN1; SMN2 (0.30)
SCHEMBL18025487 0.84 GCGR (0.34)
SCHEMBL28913708 0.84
SCHEMBL24834493 0.83 POLB (0.31) POLB
SCHEMBL21322546 0.80 DRD4 (0.38) POLB
SCHEMBL16026415 0.80 POLB (0.30) POLB
SCHEMBL31549436 0.80 POLB (0.30) POLB
SCHEMBL28909665 0.80 FOLH1 (0.33) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2415741-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2012-02-08 EP disclosed
EP-2415742-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR Sumitomo Chemical Company, Limited (JP) 2012-02-08 EP disclosed
US-20120029195-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-02 US disclosed
US-20120010417-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed
CN-1226258-C Process for producing fluorinated methyl-benzyl alcohol SHOWAN DENKO K K (JP) 2005-11-09 CN disclosed
US-6828467-B2 Industrial process of the hydrogenolysis of one hydroxyl or methanol group of a fluorinated benzenedimethanol carried out in a solvent in the presence of a catalyst; 2,3,5,6-tetra-fluorobenzyl alcohol from the 4-methyl derivative SHOWA DENKO K.K. (JP) 2004-12-07 US disclosed
EP-1322584-B1 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL SHOWA DENKO KK (JP) 2004-11-24 EP disclosed
US-20040010167-A1 Process for producing fluorinated methyl-benzyl alcohol SHOWA DENKO K.K. (JP) 2004-01-15 US disclosed
CN-1466560-A Process for producing fluorinated methyl-benzyl alcohol �Ѻ͵繤��ʽ���� 2004-01-07 CN disclosed
EP-1322584-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL Showa Denko K.K. (JP) 2003-07-02 EP disclosed
WO-2002026678-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL SHOWA DENKO K.K. (JP) 2002-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040010167-A1 Process for producing fluorinated methyl-benzyl alcohol ADH1C, ADH5, ADH1A POLB 779/4885
US-20120010417-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND ADH1A, ADH1C, ADH5 POLB 589/4885
US-20120029195-A1 METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR ADH1A, ADH1C, ADH5 POLB 1648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.