Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009544 | 1.00 | FFAR4 (0.40) | FFAR4CD274PDCD1LG2BACE1SCN9A | |
| SCHEMBL27780041 | 0.81 | FFAR4 (0.46) | FFAR4CD274BACE1SCN9AMETAP2 | |
| SCHEMBL2004116 | 0.81 | FFAR4 (0.46) | FFAR4CD274BACE1SCN9AMETAP2 | |
| SCHEMBL5230201 | 0.74 | FFAR4 (0.45) | FFAR4BACE1SCN9AMETAP2FYN | |
| SCHEMBL5231980 | 0.71 | ADRB2 (0.41) | FFAR4KCNH2 | |
| SCHEMBL2006705 | 0.71 | ADRB2 (0.41) | FFAR4KCNH2 | |
| SCHEMBL30980806 | 0.70 | DYRK1A (0.41) | CD274PDCD1LG2BACE1LMNATP53 | |
| SCHEMBL11890406 | 0.69 | TSHR (0.43) | CD274PDCD1LG2PDCD1LMNA | |
| SCHEMBL27827494 | 0.69 | TGFBR1 (0.58) | FYNTGFBR1 | |
| SCHEMBL2002809 | 0.68 | LMNA (0.44) | LMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149577-A1 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149577-A1 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | NR3C1, NR3C2, MC2R | FFAR4 84/4885CD274 3460/4885PDCD1LG2 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.