Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225666 | 0.82 | NPBWR1 (0.43) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5228692 | 0.80 | CYP1A2 (0.47) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5230220 | 0.79 | NPBWR1 (0.40) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5228410 | 0.79 | PTGS1 (0.49) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5226619 | 0.78 | NPBWR1 (0.47) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5224717 | 0.76 | NPBWR1 (0.45) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5232263 | 0.74 | SMO (0.49) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5224302 | 0.74 | SMO (0.49) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5229004 | 0.73 | NPBWR1 (0.40) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5230456 | 0.73 | SMO (0.46) | MAPTKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |