Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 6/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231215 | 0.90 | VCAM1 (0.40) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5228751 | 0.87 | NR1H3 (0.45) | VCAM1KMT2AALDH1A1HPGDALOX15 | |
| SCHEMBL5235312 | 0.81 | RORC (0.50) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5230003 | 0.77 | PGR (0.51) | PGRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1939772 | 0.75 | VCAM1 (0.44) | VCAM1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1938669 | 0.74 | VCAM1 (0.46) | VCAM1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5478547 | 0.73 | LMNA (0.54) | VCAM1MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL5237280 | 0.73 | CES1 (0.49) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL5225890 | 0.73 | VCAM1 (0.49) | VCAM1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5229337 | 0.72 | CYP19A1 (0.44) | PGRMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |