Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230003 | 0.87 | PGR (0.51) | KMT2AMEN1LMNAMAPTNPSR1 | |
| SCHEMBL5232320 | 0.82 | PTPN1 (0.48) | CYP19A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL5227868 | 0.77 | PGR (0.54) | KMT2AMEN1LMNAMAPTNPSR1 | |
| SCHEMBL5235312 | 0.75 | RORC (0.50) | KMT2AMEN1MAPTNPSR1PSEN1 | |
| SCHEMBL5228751 | 0.74 | NR1H3 (0.45) | KMT2ALMNAMAPTNR1H3ALDH1A1 | |
| SCHEMBL5229096 | 0.74 | KMT2A (0.46) | CYP19A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL5230626 | 0.72 | VCAM1 (0.42) | KMT2AMEN1MAPTALDH1A1PGR | |
| SCHEMBL5478547 | 0.71 | LMNA (0.54) | KMT2AMEN1LMNAMAPTNPSR1 | |
| SCHEMBL5227914 | 0.70 | CDK1 (0.53) | KMT2AMEN1LMNAMAPTNPSR1 | |
| SCHEMBL5231680 | 0.68 | KCNA5 (0.52) | KMT2AMEN1LMNAMAPTNR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |