Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16443508 | 0.88 | GRIN2B (0.67) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| Iodide SCHEMBL11584596 | 0.77 | GRIN2B (0.62) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| Iodide SCHEMBL11584597 | 0.77 | GRIN2B (0.62) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8471459 | 0.77 | GRIN2B (0.67) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL5269588 | 0.76 | GRIN2D (0.53) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL3074325 | 0.74 | GRIN2D (0.54) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL3069092 | 0.73 | GRIN2D (0.53) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL6313280 | 0.72 | GAA (0.41) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL3067635 | 0.70 | GRIN1 (0.62) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL3067630 | 0.70 | GRIN1 (0.62) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218337-B1 | SYNTHESIS OF 3,5,7|-1H-IMIDAZO 1,5-A|IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INST (US) | 2007-10-31 | — | — | EP | claimed |
| US-6861523-B2 | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2005-03-01 | — | — | US | claimed |
| US-6664282-B2 | For preparing and using libraries of compounds as well as individual compounds of the libraries; for screening compounds for combinatorial chemistry | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2003-12-16 | — | — | US | claimed |
| US-20030186320-A1 | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2003-10-02 | — | — | US | claimed |
| US-20050112693-A1 | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof | NEFZI ADEL (US) | 2005-05-26 | — | — | US | disclosed |
| US-6861523-B2 | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2005-03-01 | — | — | US | disclosed |
| US-6664282-B2 | For preparing and using libraries of compounds as well as individual compounds of the libraries; for screening compounds for combinatorial chemistry | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2003-12-16 | — | — | US | disclosed |
| US-20030186320-A1 | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2003-10-02 | — | — | US | disclosed |
| US-6441172-B1 | DI- AND TRI-SUBSTITUTED-1,4-DIAZACYCLIC COMPOUNDS | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2002-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186320-A1 | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries | CDK15, CUL5, UTS2R | GRIN2B 1997/4885GRIN1 1039/4885GRIN2D 1344/4885 |
| US-20050112693-A1 | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof | DHPS, DCK, DAZAP1 | GRIN2B 1838/4885GRIN1 843/4885GRIN2D 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.