Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.33 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337031 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HPGDKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL5229259 | 0.69 | NR1H2 (0.43) | ALDH1A1HPGDKMT2ASIGMAR1 | |
| SCHEMBL5340268 | 0.68 | ALDH1A1 (0.54) | ALDH1A1HPGDKMT2AKDM4ERAB9A | |
| SCHEMBL5318072 | 0.64 | MAOA (0.37) | KMT2ARAB9ASMN1; SMN2PPARGLMNA | |
| SCHEMBL5226141 | 0.63 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL11712411 | 0.58 | ALDH1A1 (0.48) | ALDH1A1HPGDKMT2AKDM4ENPC1 | |
| SCHEMBL10090415 | 0.57 | LMNA (0.64) | ALDH1A1HPGDKMT2AKDM4ENPC1 | |
| SCHEMBL11315303 | 0.57 | CASR (0.50) | ALDH1A1HPGDKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7933564 | 0.57 | SIGMAR1 (0.73) | KMT2AKDM4ESMN1; SMN2LMNASIGMAR1 | |
| SCHEMBL12886696 | 0.57 | ALDH1A1 (0.77) | ALDH1A1HPGDKMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312213-B2 | Substituted benzo[e][1,4]oxazino[3,2-g]isoindole compounds | LES LABORATORIES SERVIER (FR) | 2007-12-25 | — | — | US | disclosed |
| EP-1556387-B1 | SUBSTITUTED BENZOL E| 1,4| OXAZINO 3,2-G| ISOINDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-04-04 | — | — | EP | disclosed |
| US-20060003997-A1 | Substituted benzo[e] [1,4] oxazino [3,2-g] isoindole compounds | LES LABORATOIRES SERVIER (FR) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060003997-A1 | Substituted benzo[e] [1,4] oxazino [3,2-g] isoindole compounds | H1-3, H1-0, H1-2 | ALDH1A1 161/4885HPGD 829/4885KMT2A 2620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.