Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 9/20 | 0.32 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226141 | 0.89 | SIGMAR1 (0.39) | MAOASIGMAR1BCHEACHE | |
| SCHEMBL5228985 | 0.78 | MAOA (0.35) | MAOASIGMAR1BCHEACHE | |
| SCHEMBL5226351 | 0.73 | MPO (0.40) | — | |
| Hydrochloric Acid SCHEMBL5412040 | 0.72 | MPO (0.40) | XDH | |
| SCHEMBL5230537 | 0.71 | MPO (0.42) | KMT2AMEN1XDHSMN1; SMN2 | |
| SCHEMBL5421563 | 0.69 | SIGMAR1 (0.38) | SIGMAR1KMT2AL3MBTL1KDR | |
| SCHEMBL5229259 | 0.66 | NR1H2 (0.43) | SIGMAR1KMT2AL3MBTL1KDR | |
| SCHEMBL5333498 | 0.64 | MPO (0.44) | SIGMAR1KMT2AMEN1XDHSMN1; SMN2 | |
| SCHEMBL5231971 | 0.64 | ALDH1A1 (0.34) | SIGMAR1PPARGKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL5334632 | 0.61 | CDK4 (0.44) | MAOARAB9AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556387-B1 | SUBSTITUTED BENZOL E| 1,4| OXAZINO 3,2-G| ISOINDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-04-04 | — | — | EP | claimed |