Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238186 | 0.86 | CYP2C19 (0.43) | USP2ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL5236779 | 0.84 | HDAC8 (0.39) | USP2ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL5237974 | 0.84 | RXRA (0.44) | USP2ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL5235440 | 0.84 | ALDH1A1 (0.40) | USP2ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL5234836 | 0.84 | MEN1 (0.43) | RAB9AUSP2ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL5232372 | 0.83 | ALDH1A1 (0.41) | RAB9AUSP2ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL5232200 | 0.83 | SLC6A7 (0.42) | USP2ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL5238500 | 0.82 | KMT2A (0.44) | RAB9AALDH1A1HSD17B10ALOX15KMT2A | |
| SCHEMBL5236995 | 0.82 | KMT2A (0.42) | RAB9AALDH1A1HSD17B10ALOX15KMT2A | |
| SCHEMBL5237657 | 0.81 | KCNA5 (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |