Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233064 | 0.84 | L3MBTL1 (0.48) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL5237657 | 0.84 | KCNA5 (0.39) | TP53SMN1; SMN2 | |
| SCHEMBL5234836 | 0.83 | MEN1 (0.43) | KMT2AMEN1MAPTALDH1A1ALOX15 | |
| SCHEMBL5235440 | 0.83 | ALDH1A1 (0.40) | KMT2AMEN1MAPTALDH1A1ALOX15 | |
| SCHEMBL5232372 | 0.82 | ALDH1A1 (0.41) | KMT2AMEN1MAPTALDH1A1ALOX15 | |
| SCHEMBL5232202 | 0.82 | RAB9A (0.40) | KMT2AMEN1MAPTALDH1A1ALOX15 | |
| SCHEMBL5236998 | 0.81 | KMT2A (0.40) | KMT2AMEN1MAPTALDH1A1ALOX15 | |
| SCHEMBL5238186 | 0.80 | CYP2C19 (0.43) | KMT2AMEN1MAPTALDH1A1HSD17B10 | |
| SCHEMBL5235107 | 0.80 | MAPT (0.45) | KMT2AMEN1MAPTALDH1A1TP53 | |
| SCHEMBL5239092 | 0.79 | MEN1 (0.41) | KMT2AMEN1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |