Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232906 | 0.80 | HIF1A (0.47) | KIF11KMT2AHSD11B1CES1CYP3A4 | |
| SCHEMBL20346302 | 0.73 | LMNA (0.47) | LMNAKIF11HPGDMEN1KMT2A | |
| SCHEMBL2060134 | 0.73 | CNR2 (0.52) | LMNAKIF11CES2ACHECES1 | |
| SCHEMBL1183571 | 0.72 | ESR1 (0.53) | LMNAHPGDKMT2AHSD17B10CYP3A4 | |
| SCHEMBL18286244 | 0.71 | FFAR1 (0.43) | LMNAKIF11HPGDMEN1KMT2A | |
| SCHEMBL17515298 | 0.70 | LMNA (0.43) | LMNAKIF11HPGDMEN1KMT2A | |
| SCHEMBL2444390 | 0.69 | LMNA (0.45) | LMNAKIF11HPGDMEN1KMT2A | |
| SCHEMBL1653535 | 0.69 | KIF11 (0.45) | LMNAKIF11KMT2AHSD11B1PARP1 | |
| SCHEMBL8034200 | 0.69 | HIF1A (0.47) | KMT2ACES1CYP2D6CYP2C19TDP1 | |
| SCHEMBL2441927 | 0.69 | LMNA (0.49) | LMNAKIF11HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197463-B1 | USED IN PRINTER AND COPIERS; WEAR RESISTANCE; PRINTING RESISTANCE; DURABILITY | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-03-06 | — | — | US | disclosed |
| US-6017665-A | CHARGE GENERATION LAYER COATED ONTO A SUBSTRATE FROM A COATING SOLUTION CONTAINING BINDER, CHARGE GENERATING MATERIAL, AND AN ORGANOSILANE COMPOUND; ADHESION, DURABILITY | MITSUBISHI CHEMICAL AMERICA (US) | 2000-01-25 | — | — | US | disclosed |