Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1174126 | 0.98 | LTA4H (0.55) | LTA4HTSHRMAOBAKR1C3HDAC8 | |
| SCHEMBL6842201 | 0.83 | MAPT (0.45) | TSHRAKR1C3MEN1MITFALDH1A1 | |
| SCHEMBL3759340 | 0.83 | MAOA (0.47) | MAOBAKR1C3MEN1MITFALDH1A1 | |
| SCHEMBL22559 | 0.82 | LTA4H (0.75) | LTA4HTSHRMAOBAKR1C3HDAC8 | |
| SCHEMBL30211827 | 0.82 | LTA4H (0.75) | LTA4HTSHRMAOBAKR1C3HDAC8 | |
| SCHEMBL380685 | 0.82 | LTA4H (0.75) | LTA4HTSHRMAOBAKR1C3HDAC8 | |
| SCHEMBL4025817 | 0.82 | LTA4H (0.75) | LTA4HTSHRMAOBAKR1C3HDAC8 | |
| SCHEMBL30018242 | 0.82 | LTA4H (0.75) | LTA4HTSHRMAOBAKR1C3HDAC8 | |
| SCHEMBL1173711 | 0.82 | LTA4H (0.75) | LTA4HTSHRMAOBAKR1C3HDAC8 | |
| SCHEMBL1173869 | 0.82 | LTA4H (0.75) | LTA4HTSHRMAOBAKR1C3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257408-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-08-17 | — | — | US | disclosed |
| EP-4186882-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-05-31 | — | — | EP | disclosed |
| CN-115836041-A | Process for producing optically active compound | 住友化学株式会社 | 2023-03-21 | — | — | CN | disclosed |
| CN-105189524-B | The synthetic method of optical activity alpha-amino acid | 浜理药品工业株式会社 | 2019-07-19 | — | — | CN | disclosed |
| US-10059700-B2 | Supported catalyst for aldehyde coupling reaction , method for performing aldehyde coupling reaction, and method for regenerating supported catalyst for aldehyde coupling reaction | SEKISUI CHEMICAL CO., LTD. (JP) | 2018-08-28 | — | — | US | disclosed |
| EP-3006449-B1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE ALPHA-AMINO ACID USING CHIRAL METAL COMPLEX COMPRISING AXIALLY CHIRAL N-(2-ACYLARYL)-2-[5,7-DIHYDRO-6H-DIBENZO[C,E]AZEPIN-6-YL]ACETAMIDE COMPOUND AND AMINO ACID | HAMARI CHEMICALS LTD (JP) | 2018-01-31 | — | — | EP | disclosed |
| US-9695112-B2 | Method for synthesizing optically active α-amino acid using chiral metal complex comprising axially chiral N-(2-acylaryl)-2-[5,7-dihydro-6H-dibenzo[c,e]azepin-6-yl] acetamide compound and amino acid | HAMARI CHEMICALS, LTD. (JP) | 2017-07-04 | — | — | US | disclosed |
| CN-104109150-B | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | 日本曹达株式会社 | 2017-04-12 | — | — | CN | disclosed |
| WO-2016195115-A1 | SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION, METHOD FOR PERFORMING ALDEHYDE COUPLING REACTION, AND METHOD FOR REGENERATING SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION | SEKISUI CHEMICAL CO., LTD. (JP) | 2016-12-08 | — | — | WO | disclosed |
| US-20160346774-A1 | SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION , METHOD FOR PERFORMING ALDEHYDE COUPLING REACTION, AND METHOD FOR REGENERATING SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION | SEKISUI CHEMICAL CO., LTD. (JP) | 2016-12-01 | — | — | US | disclosed |
| US-5104559-A | Lubricants or oil additives | THE DOW CHEMICAL COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0163895-B1 | PROCESS FOR THE DIASTEREOSELECTIVE REDUCTION OF ALPHA-TRIAZOLYL KETONES TO BETA-TRIAZOLYL CARBINOLS | BASF Aktiengesellschaft (DE) | 1989-04-12 | — | — | EP | disclosed |
| US-4748250-A | Diastereoselective reduction of alpha-triazolylketones to betatriazolylcarbinols | BASF AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| EP-0090312-B1 | 3-ACYL SUBSTITUTED DERIVATIVES OF 2- OR 4-THIAZOLIDINE-CARBOXYLIC ACID HAVING A PHYTO GROWTH REGULATING AND BIOSTIMULATING ACTION | Montedison S.p.A. (IT) | 1987-09-09 | — | — | EP | disclosed |
| US-4685954-A | 3-acyl substituted of 2- or 4-thiazolidine-carboxylic acid having a phyto growth regulating and biostimulating action | MONTEDISON S.P.A (IT) | 1987-08-11 | — | — | US | disclosed |
| US-4655818-A | 3-acyl substituted derivatives of 2- or 4-thiazolidine-carboxylic acid having a phyto growth regulating and biostimulating action | MONTEDISON S.P.A. (IT) | 1987-04-07 | — | — | US | disclosed |
| EP-0163895-A1 | Process for the diastereoselective reduction of alpha-triazolyl ketones to beta-triazolyl carbinols | BASF Aktiengesellschaft (DE) | 1985-12-11 | — | — | EP | disclosed |
| EP-0090312-A2 | 3-Acyl substituted derivatives of 2- or 4-thiazolidine-carboxylic acid having a phyto growth regulating and biostimulating action | Montedison S.p.A. (IT) | 1983-10-05 | — | — | EP | disclosed |
| EP-0018324-A1 | Herbicidal, substituted diphenyl-ether derivatives, process for their preparation, as well as herbicidal compositions and their use | CIBA-GEIGY AG (CH) | 1980-10-29 | — | — | EP | disclosed |
| US-3939084-A | Functional fluid compositions containing substituted pyrimidines | MONSANTO COMPANY (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257408-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND | SIRT1, SIRT3, HCCS | LTA4H 3612/4885TSHR 688/4885MAOB 1073/4885 |
| US-20160346774-A1 | SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION , METHOD FOR PERFORMING ALDEHYDE COUPLING REACTION, AND METHOD FOR REGENERATING SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION | ALDH2, ALDH7A1, ALDH3A1 | LTA4H 1051/4885TSHR 1261/4885MAOB 785/4885 |
| US-10059700-B2 | Supported catalyst for aldehyde coupling reaction , method for performing aldehyde coupling reaction, and method for regenerating supported catalyst for aldehyde coupling reaction | ALDH2, ALDH7A1, ALDH3A1 | LTA4H 1051/4885TSHR 1261/4885MAOB 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.