Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231726 | 0.91 | GRM4 (0.44) | GRM4MEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL4872056 | 0.85 | CYP1A2 (0.55) | GRM4KMT2AL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL3747756 | 0.83 | ALDH1A1 (0.39) | NPC1GAAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL31461243 | 0.83 | ALDH1A1 (0.39) | NPC1GAAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5236574 | 0.78 | TSHR (0.48) | GRM4KMT2AL3MBTL1CYP1A2SMN1; SMN2 | |
| SCHEMBL22122307 | 0.77 | SLC22A12 (0.47) | L3MBTL1ALDH1A1MAPTKDM4ESLC22A12 | |
| SCHEMBL5232920 | 0.75 | RAB9A (0.49) | GRM4MEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL5238502 | 0.75 | GRM5 (0.34) | MEN1KMT2ANPC1GAAALDH1A1 | |
| SCHEMBL5238497 | 0.75 | GRM5 (0.34) | MEN1KMT2ANPC1GAAALDH1A1 | |
| SCHEMBL5231287 | 0.74 | NPC1 (0.49) | GRM4MEN1KMT2ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397364-B1 | NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | LILLY CO ELI (US) | 2007-07-25 | — | — | EP | disclosed |