Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 3/20 | 0.48 |
| ▸ | MMP7 | P09237 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346677 | 0.83 | MMP1 (0.54) | ALDH1A1MMP1MMP3MMP7MMP9 | |
| SCHEMBL751771 | 0.74 | HSD11B1 (0.54) | ALDH1A1 | |
| SCHEMBL6189161 | 0.74 | CACNA2D1 (0.49) | ALDH1A1MMP1MMP3MMP7MMP9 | |
| SCHEMBL695071 | 0.73 | MMP2 (0.59) | ALDH1A1MMP9GAAHTT | |
| SCHEMBL17833176 | 0.73 | MMP2 (0.59) | ALDH1A1MMP9GAAHTT | |
| SCHEMBL1382978 | 0.72 | SMN1; SMN2 (0.53) | ALDH1A1MMP1MMP3MMP7MMP9 | |
| SCHEMBL8718942 | 0.72 | LMNA (0.58) | ALDH1A1MMP9USP2HTT | |
| SCHEMBL4035557 | 0.71 | MMP1 (0.62) | ALDH1A1MMP1MMP3MMP7MMP9 | |
| SCHEMBL4037002 | 0.71 | MMP1 (0.62) | ALDH1A1MMP1MMP3MMP7MMP9 | |
| SCHEMBL4038681 | 0.71 | MMP1 (0.62) | ALDH1A1MMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200824-B1 | SOLID PHASE SYNTHESIS OF N,N-DISUBSTITUTED DIAZACYCLOALKYLCARBOXY DERIVATIVES | AVENTIS PHARMA INC (US) | 2007-04-25 | — | — | EP | disclosed |
| US-7138526-B1 | Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives | AVENTIS PHARMACEUTICALS INC. (US) | 2006-11-21 | — | — | US | disclosed |
| EP-1200824-A4 | SOLID PHASE SYNTHESIS OF N,N-DISUBSTITUTED DIAZACYCLOALKYLCARBOXY DERIVATIVES | AVENTIS PHARM PROD INC (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1200824-A1 | SOLID PHASE SYNTHESIS OF N,N-DISUBSTITUTED DIAZACYCLOALKYLCARBOXY DERIVATIVES | Aventis Pharmaceuticals Products Inc. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2000077519-A1 | SOLID PHASE SYNTHESIS OF N,N-DISUBSTITUTED DIAZACYCLOALKYLCARBOXY DERIVATIVES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-12-21 | — | — | WO | disclosed |