Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233237 | 0.89 | SMN1; SMN2 (0.44) | MGLLDGAT1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL5237020 | 0.85 | MGLL (0.47) | MGLLSLC6A7WNT3ADGAT1MAPT | |
| SCHEMBL5234482 | 0.83 | MGLL (0.46) | MGLLSLC6A7DGAT1KCNH2GRIN2B | |
| SCHEMBL5236708 | 0.83 | KDM1A (0.41) | SLC6A7MAPTSMN1; SMN2 | |
| SCHEMBL5233010 | 0.80 | MGLL (0.44) | MGLLSLC6A7WNT3ADGAT1KDM4E | |
| SCHEMBL5237027 | 0.79 | MGLL (0.44) | MGLLSLC6A7WNT3ADGAT1BRAF | |
| SCHEMBL5232330 | 0.79 | MGLL (0.64) | MGLLSLC6A7WNT3ADGAT1MAPT | |
| SCHEMBL5237745 | 0.75 | MGLL (0.60) | MGLLSLC6A7MAPTSMN1; SMN2KDM4E | |
| SCHEMBL5238349 | 0.74 | MAPT (0.45) | MGLLDGAT1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL5233015 | 0.74 | MGLL (0.42) | MGLLSLC6A7DGAT1KCNH2GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |